Comparison of two drugs( Gabapentin and Memantine) as supplements for pain relief in laparoscopic surgery

Comparison of efficacy of Preoperative use of Gabapentin and Memantine as Adjuvants to Analgesia with no Adjuvants in laproscopic Cholecystectomies for acute Postoperative pain relief -A Randomised control trial

Status

Active, not recruiting

Phases

Phase 2Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2018/07/014852

Enrollment

Registered

2018-07-13

Start date

Unknown

Completion date

Unknown

Last updated

2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical Health Condition 2: null- normal patients, controlled hypertensives, controlled diabetics, controlled hypothyroid or hyperthyroid

Interventions

Intervention1: Comparison of efficacy of Preoperative use of Gabapentin and Memantine as Adjuvants to Analgesia with no Adjuvants in laproscopic Cholecystectomies for acute Postoperative pain relief -

Eligibility

Inclusion criteria

Inclusion criteria: ASA Grade 1&2 Age 18-70 years Laproscopic cholecystectomy surgery Adequately controlled diabetics and hypertensives

Exclusion criteria

Exclusion criteria: Age 70years Pregnancy Uncontrolled diabetics and hypertensives Obesity or H/o obstructive sleep apnoea

Design outcomes

Primary

Measure	Time frame
preoperative use of gabapentin and memantine as premediction would decrease post operative pain relief compared to placeboTimepoint: pre anaesthetic checkup to 4hrs after Extubation	—

Secondary

Measure	Time frame
any adverse effects of drugsTimepoint: pre anaesthetic checkup to 4hrs after Extubation	—

Countries

India

Contacts

Public ContactDrJKavitha

Nizams Institute of Medical Sciences

drkarunya@gmail.com8143769301

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026