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Comparitive study of two antiemetic drugs group to decrease the chances of emesis after Laproscopic Cholecyestectomy

"Comparative Evaluation Of Two Antiemetic Combination OF Palenosetron-Dexamethasone Versus Granisetron-Dexamethasone in Patients Undergoing Elective Laproscopic Surgery"

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2018/07/014830
Enrollment
84
Registered
2018-07-12
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- SYMPTOMATIC CHOLILITHIASIS FOR LAPROSCOPIC SURGERIES

Interventions

Intervention1: To evaluate the safety and efficacy of polanosetron-dexamethasone with granisetron-dexamethasone for ponv in patients undergoing laparoscopic Cholecystectom : IV 0.075mg ofpalon

Sponsors

Dr RPGMC TANDA
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Patients in the age group of 20-60 years. 1.ASA I â??II 2.Patient willing to give consent for study. 3.No history of motion sickness. 4.No previous history of PONV. 5.Nonsmoker.

Exclusion criteria

Exclusion criteria: 1. Patients not giving consent for study. 2. Patients with history of taking drugs responsible for antiemetic action for eg. steroids etc. 3. Smoker. 4. Patient with gastrointestinal reflux diseases. 5. Patient with history of PONV or motion sickness and those who had allergy to the study drugs or received antiemetic within 48 h before surgery. 6. Pregnancy and lactation. 7. Body mass index >35 kg/m2. 8. Patients with Baseline prolonged QTc interval. 9. Patients with electrolyte imbalances.

Design outcomes

Primary

MeasureTime frame
To evaluate the safety and efficacy of polanosetron-dexamethasone with granisetron-dexamethasone for ponv in patients undergoing laparoscopic Cholecystectom Timepoint: 72 HOURS

Secondary

MeasureTime frame
Patient Satisfaction scoreTimepoint: 72 hours

Countries

India

Contacts

Public ContactDr Ashish Minhas

Dr.R.P.G.M.C TANDA HIMACHAL PRADESH

drjaisingh62@gmail.com9418070893

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026