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Yoga and Type 2 Diabetes Mellitus - a molecular perspective

Role of yoga and its possible mechanism involved in Type 2 Diabetes Mellitus related DNA damage and repair - A Randomized Controlled Trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2018/07/014825
Enrollment
70
Registered
2018-07-12
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- Type 2 Diabetes Mellitus Health Condition 2: E119- Type 2 diabetes mellitus without complications

Interventions

Intervention1: Yoga group: This group will be provided with yoga practices. Asana, Pranayama, Meditation practices for 1 hr daily for one month Control Intervention1: Control group: Usual daily routin

Sponsors

University Grant Commision
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Patients identified with T2DM [6.5 Fasting Plasma glucose above 126 mg/dL Age ranging from 35 to 60 from both gender Willingness to participate in a 4 - week yoga program

Exclusion criteria

Exclusion criteria: Type 1 Diabetes Mellitus Uncontrolled diabetes and hypertension, Cardiovascular diseases Morbid obesity Cancer Neurological or Psychological disorders Mobility restrictions or inability to do Yoga practices Alcoholic, or addiction to any forms of drug usage Recent major trauma or surgery that would interfere with participation Pregnant women Unable to provide informed consent Persons not versed with English or Kannada or Hindi

Design outcomes

Primary

MeasureTime frame
DNA damage in Lymphocytes Protein quantification: ATM, ATR, CHK1, CHK2, BRCA1, BRCA2, p53 Gene expression: p73 Oxidative DNA damage marker Antioxidant marker: Total Antioxidant Capacity (TAC) Oxidative stress markers: Malondialdehyde (MDA Timepoint: before and after the intervention—

Secondary

MeasureTime frame
Fasting Blood Sugar (FBS) Post Prandial Blood Sugar (PPBS) HbA1C: Glycated Haemoglobin Blood Pressure: (Systolic / Diastolic) AnthropometricsTimepoint: Before and after the intervention—

Countries

India

Contacts

Public ContactRajesh G Nair

SVYASA university

rajeshindit@gmail.com

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 15, 2026