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To evaluate beneficial effects of Dexmeditomidine on stress of surgery

Attenuation of sympathoadrenal responses with dexmedetomidine in elective off-pump CABG

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2018/07/014814
Enrollment
60
Registered
2018-07-11
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- ASA grade 2 and 3 Health Condition 2: I999- Unspecified disorder of circulatory system

Interventions

Intervention1: dexmedetomidine: Group D: Patient received loading dose of dexmedetomidine 1 mcq/kg diluted in 100ml 0.9% normal saline over 10 minutes IV. than maintenance of dexmedetomidine 0.5mcq/kg

Sponsors

NIL
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. Patients belonging to ASA Grade II & III 2. Patients undergoing elective off pump CABG

Exclusion criteria

Exclusion criteria: 1. Patientâ??s age > 75 yr 2. ASA grade I & IV 3. BMI > 30kg/m2 4. Ejection Fraction 5. Left Main Coronary Artery occlusion > 50 % 6. Valvular dysfunction 7. Preoperative LBBB 8. Severe systemic disorder like IDDM, kidney or liver insufficiency and severe respiratory disorder. 9. Intubation attempt lasting longer than 20 seconds or difficult intubation.

Design outcomes

Primary

MeasureTime frame
HR, SBP, DBP, MBPTimepoint: 1,3, 5 minute after Intubation, incision and sternotomy—

Secondary

MeasureTime frame
Any side effectsTimepoint: till end of surgery;Total dose of Thiopentone for induction Timepoint: Till BIS score achieved between 40-50—

Countries

India

Contacts

Public ContactDr Deepa Agarwal

Dr. S.N. medical collage, Jodhpur

geetamanojkamal@gmail.com9414803554

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026