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A study to compare additional treatment with Subconjunctival and Topical Bevacizumab (a drug known to reduce recurrence in various studies) combined with Pterygium surgery versus Pterygium surgery alone on recurrence of pterygium : A multi centric trial

Comparative study of adjunctive treatment with Subconjunctival and Topical Bevacizumab combined with Pterygium excision and conjunctival autograft versus Pterygium excision with conjunctival autograft alone on recurrence after excision of primary pterygium : A multi centric trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2018/07/014812
Enrollment
1749
Registered
2018-07-11
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- Patients of Pterygium who meet the inclusion criteria and give their consent for trial

Interventions

Intervention1: Pterygium Excision and conjunctival autograft.: This is Standard of care. Patients will undergo Pterygium Excision and conjunctival autograft using fibrin glue Control Intervention1: Pt

Sponsors

Office of DGAFMS Ministry of Defence
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Primary Pterygium extending >2 mm into cornea

Exclusion criteria

Exclusion criteria: ï?? Previous limbal surgery/recurrent pterygium ï?? Ocular surface disease ï?? Any ocular infection ï?? Autoimmune disorders ï?? Pregnancy ï?? Systemic contraindications for bevacizumab â?? recent history of following (in last 6 months) o Myocardial infarction o Stroke o Pulmonary embolism o Deep Vein Thrombosis o Any other thromboembolic condition

Design outcomes

Primary

MeasureTime frame
Recurrence rateTimepoint: 3 months, 6 months, 9 months and 1 year—

Secondary

MeasureTime frame
Adverse eventsTimepoint: 3 months, 6 months, 9 months and 1 year—

Countries

India

Contacts

Public ContactDr Priyanka Pantola

Indian Air Force, Ministry of Defence

priyankapantola7@gmail.com7030625714

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026