Health Condition 1: null- Children of Asthma coming to paediatric OPD Health Condition 2: J454- Moderate persistent asthma
Conditions
Interventions
Intervention1: Vitamin-D: 1.Initial evaluation included a detailed medical history and complete physical and systemic examination.
2.Spirometry with bronchodilator reversibility will be done in all
Sponsors
AIIMS Jodhpur
Eligibility
Inclusion criteria
Inclusion criteria: 1. Children 6 to 18 years of age, newly diagnosed case of asthma by Pediatrician. (Clinical and/or PFT). OR follow-up case of asthma in chest clinic at AIIMS 2. Those willing to take medication for 3 months and regular follow-up.
Exclusion criteria
Exclusion criteria: 1. Patients with history of prematurity, bronchopulmonary dysplasia, coexisting primary parenchymal pulmonary disease (e.g. cystic fibrosis) or coexisting congenital/acquired heart diseases, and patients of epilepsy on anticonvulsants. 2. Known case of Vitamin â??D deficiency. 3. History of intake of Vitamin-D and calcium in past 1 month. 4. Known case of any disease involving Vitamin-D & calcium metabolism. 5. Consent not given. 6. Those with hypercalcemia or allergy to Vitamin- D.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1. Primary outcome measure will be ACT score (which is a validated score and contained 5 items with minimum score of 5 to maximum score of 25) at 3 monthsTimepoint: 1. Enrollment will be done in 1st 3 months 2. Interventions will start at the time of enrollment. 3. Participants will be asked to visit clinic after every 15 days for follow-up. | — |
Secondary
| Measure | Time frame |
|---|---|
| Secondary outcome measure will be FEV1, fraction excretion of nitric oxide, number of asthma exacerbation, serum 25-OH vitamin D3 at 3 months and adverse outcome, no. of emergency visits, use of systemic steroid.Timepoint: 1. Enrollment will be done in 1st 3 months 2. Interventions will start at the time of enrollment. 3. Participants will be asked to visit clinic after every 15 days for follow-up. | — |
Countries
India
Contacts
Public ContactDr Chirag Thakur
AIIMS, Jodhpur
Outcome results
None listed