Efficacy of two medicaments in pain response and bleeding status in lower molars.

Efficacy analysis of two pulp devitalizing agent containing paraformaldehyde in pain response and bleeding status in mandibular molars. - EAPDAPPBMM

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2018/07/014758

Enrollment

Registered

2018-07-06

Start date

Unknown

Completion date

Unknown

Last updated

2022-10-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: 8- Other Procedures Health Condition 2: null- Patients with a clinical diagnosis of irreversible pulpitis in mandibular molars

Interventions

Intervention1: Caustinerf: Paraformaldehyde and lidocaine based pulp devitalising agent Intervention2: D-pulp: Paraformaldehyde based pulp devitalising agent

Eligibility

Inclusion criteria

Inclusion criteria: Patients with clinical diagnosis of irreversible pulpitis in mandibular molars, i.e, participants experiencing moderate to severe pain even after administration of local anaesthesia and exhibiting a positive response to the electric pulp test and cold test with Endo-ice.

Exclusion criteria

Exclusion criteria: 1. The subjects who are under medication that would alter pain perception as determined by oral questioning and written questionnaire. 2. Presence of any periapical pathology on radiographs.

Design outcomes

Primary

Measure	Time frame
Reduction in pain during the subsequent endodontic procedureTimepoint: After 24 hours.	—

Secondary

Measure	Time frame
Reduction in bleeding during the subsequent endodontic procedureTimepoint: After 24 hours.	—

Countries

India

Contacts

Public ContactNaomi Ranjan Singh

Institute of Dental Sciences

singhnaomi23@gmail.com9937230101

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026