Clinical study of propofol and dexmedetomidine for hypotensive anaesthesia.

A comparative evaluation of propofol and dexmedetomidine for hypotensive anaesthesia during functional endoscopic sinus surgery

Status

Active, not recruiting

Phases

Phase 3Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2018/07/014746

Enrollment

Registered

2018-07-05

Start date

Unknown

Completion date

Unknown

Last updated

2022-10-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- elective functional endoscopic sinus surgery

Interventions

Intervention1: propofol and dexmedetomidine infusions: propofol infusion @100-200 microgram/kg/min, from 10 min before surgery to 20 min before end of surgery. dexmedetomidine infusion @0.4-0.8 microg

Eligibility

Inclusion criteria

Inclusion criteria: aged 18 to 50 years ASA grade 1 and 2 patient elective surgery

Exclusion criteria

Exclusion criteria: patient refusal h/0 anaphylaxis to any of the study drug uncontrolled hypertension coagulation disorder ASA grade 3 and 4 pregnant patient

Design outcomes

Primary

Measure	Time frame
blood loss during surgery. quality of surgical field. haemodynamic changesTimepoint: blood loss during surgery measured during 2-2.5 hour surgery quality of surgical field during operative intervention inside sinuses i.e. 1 hour. haemodynamic changes during 2- 2.5 hours surgery.	—

Secondary

Measure	Time frame
haemodynamic changesTimepoint: surgery duration	—

Countries

India

Contacts

Public ContactDr Kewal Krishan Gupta

Guru gobind singh medical college and hospital, faridkot

doc_krishan31@yahoo.co.in9988316306

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026