TO STUDY THE DIFFERENT DOSES OF INTRAVENOUS DEXMEDETOMIDINE ON BLOOD PRESSURE AND HEART RATE, DECREASE IN SUDDEN AWAKENING AT THE END OF SURGERY, INCIDENCE DIFFICULTIES IN BREATHING AND POST SURGERY SEDATION IN PAEDIATRIC PATIENTS FOLLOWING GENERAL ANAESTHESIA.

TO STUDY THE EFFECT OF DIFFERENT DOSES OF INTRAVENOUS DEXMEDETOMIDINE ON HEMODYNAMIC RESPONSE, ATTENUATION OF EMERGENCE AGITATION, INCIDENCE OF AIRWAY COMPLICATIONS AT EXTUBATION AND POST OPERATIVE SEDATION IN PAEDIATRIC PATIENTS FOLLOWING GENERAL ANAESTHESIA

Status

Active, not recruiting

Phases

Phase 1

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2018/07/014700

Enrollment

Registered

2018-07-02

Start date

Unknown

Completion date

Unknown

Last updated

2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- Those undergoing surgeries under General anaesthesia

Interventions

Intervention1: Placebo: Normal saline 10ml given intravenously over 30minutes Control Intervention1: Dexmedetomidine: 0.5mcg/kg given intravenously once over 30minutes Control Intervention2: Dexmedeto

Eligibility

Inclusion criteria

Inclusion criteria: 1. Patients of ASA12 grade I or II. 2. Paediatric age group 3 months-12 years of either gender. 3. Patient scheduled to undergo elective surgical procedure under general anaesthesia.

Exclusion criteria

Exclusion criteria: 1. Patients of ASA grade III or above. 2. Age less than 3 months and more than 12 years. 3. Patients physically dependent on narcotics. 4. Patients with history of drug allergy to Dexmedetomidine.

Design outcomes

Primary

Measure	Time frame
Heart rate, Systolic blood pressure, Diastolic blood pressure, mean arterail pressure, sedationTimepoint: Preinduction, After intubation, At dexmed infusion, At extubation, At 1, 5, 10 and 15 minutes after extubation	—

Secondary

Measure	Time frame
Too much sedation, respiratory obstruction, laryngospasm, bronchospasmTimepoint: post operative	—

Countries

India

Contacts

Public ContactDHANANJAYA B D

Rainbow childrens hospital

drskmohanty123@gmail.com9538897144

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026