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Comparison of intravenous dexmedetomidine and clonidine effect in Trans-ABdominal Hysterectomy undergoing in spinal anaesthesia given by bupivacaine

An Evaluation of the effect of intravenous dexmedetomidine and clonidine on the characteristics of subarachnoid block (SAB) by bupivacaine in Trans-ABdominal Hysterectomy (TAH). - Nil

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2018/07/014690
Enrollment
150
Registered
2018-07-02
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- Multigravida

Interventions

Intervention1: Dexmedetomidine: Loading IV 1microgram/kg for 15mins followed by infusion 0.3microgram/kg/h till end of surgery Intervention2: Clonidine: Loading IV 2microgram/kg for 15mins followed by

Sponsors

RNT Medical College
Lead Sponsor
MB Hospital
Collaborator

Eligibility

Inclusion criteria

Inclusion criteria: ASA grade I and grade II

Exclusion criteria

Exclusion criteria: ASA grade III or above BMI > 30kg/m2 Who will refuse to give consent for spinal anaesthesia History of cardiac rhythm like bradycardia or A-V junction bkock History of preoperative intake of ACE inhibitors, calcium channel blockers, beta blockers, alpha 2 adrenergic receptor antagonist

Design outcomes

Primary

MeasureTime frame
To Evaluate of the effect of Intravenous Dexmedetomidine and Clonidine on the characteristics of Subarachnoid block by Bupivacaine in Trans-Abdominal HysterectomyTimepoint: 1min, 2mins, 5mins, 10mins, 15mins, 30mins, 45mins, till end of surgery—

Secondary

MeasureTime frame
To determine the hemodynamic consquence of IV Dexmedetomidine and Clonidine administrationTimepoint: 1min, 2mins, 5mins, 10mins, 15mins, 30mins, 45mins, till end of surgery—

Countries

India

Contacts

Public Contactsonu

RNT Medical College, Udaipur

vbedimd@gmail.com9829025373

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026