Health Condition 1: null- atrial fibrillation and valve replacement patients requiring chronic anticoagulation therapy
Conditions
Interventions
Intervention1: warfarin: in adult patients suffering from atrial fibrillation and patients requiring valve replacement surgeries who require chronic anticoagulation therapy
Control Intervention1: nil:
Sponsors
Dr Nusrat Shafiq
Eligibility
Inclusion criteria
Inclusion criteria: Adult patients of atrial fibrillation and patients requiring valve replacement surgeries on chronic anticoagulation therapy with warfarin
Exclusion criteria
Exclusion criteria: 1. Patients with known contraindications to anticoagulant therapy, 2. Patients of transient atrial fibrillation secondary to reversible disorders such as thyrotoxicosis, cardiothoracic surgery and severe anaemia, 3. Patients with underlying hepatic (defined as elevation in alanine/ aspartate transaminase >2.5 times the upper limit of normal) and or severe renal insufficiency(defined as creatinine clearance of 4. Pregnant and nursing women, 5. Patients unwilling to participate in the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Stable anticoagulation controlTimepoint: INR within therapeutic range for 3 months without any dose modification | — |
Secondary
| Measure | Time frame |
|---|---|
| adverse events as reported by patientsTimepoint: at every follow up visit of the patient | — |
Countries
India
Contacts
Public ContactDr Navjot Kaur
PGIMER, Chandigarh
Outcome results
None listed