Comparison of effect of different steroids following cataract surgery

Comparison of safety and efficacy of Prednisolone acetate vs Difluprednate vs Loteprednol eyedrops post cataract surgery

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2018/06/014609

Enrollment

150

Registered

2018-06-25

Start date

Unknown

Completion date

Unknown

Last updated

2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: H25- Age-related cataract Health Condition 2: null- Patients planned for uncomplicated cataract surgery

Interventions

Intervention1: Difluprednate eyedrops: 0.05% Difluprednate eyedrops -used postoperatively - frequency 1 drop four times/ day and gradually tapered over 4 weeks Intervention2: Loteprednol eyedrops: 0

Eligibility

Inclusion criteria

Inclusion criteria: 1. patients with immature senile cataract, upto grade 3 nuclear sclerosis

Exclusion criteria

Exclusion criteria: 1. signs of uveitis, intraocular inflammation, macular edema due to previous intraocular surgery in any one of the eyes 2. Patients with diabetes, complicated cataract, nuclear sclerosismore than grade 3 3. patients with intraoperative complications 4. one eyed patients

Design outcomes

Primary

Measure	Time frame
1. ocular pain 2. intraocular pressure 3. corneal inflammation 4. anterior chamber inflammation 5.macular thicknessTimepoint: 1. Day 1 2. Day 7 3. Day 14 4. Day 28 postoperatively	—

Secondary

Measure	Time frame
NoneTimepoint: None	—

Countries

India

Contacts

Public ContactAaliya Ambereen

Chettinad Hospital & Research Institute

dr_stephen1978@yahoo.com9840821846

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026