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To study the effect of repetitive transcranial magnetic stimulation and amitryptilline on migraine headache

Evaluation of clinico-electrophysiological profile of episodic migraine and chronic daily headache patients in relation to repetitive transcranial magnetic stimulation given either alone or in combination with amytriptilline

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2018/06/014542
Enrollment
100
Registered
2018-06-15
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- primary headache

Interventions

Intervention1: repetitive transcranial magnetic stimulation(RTMS): High frequeny RTMS(10 pulses at 12 hz at 70 percent of motor threshold) three sessions on daily basis for three months Intervention2:

Sponsors

Dr Jayantee Kalita
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: primary headache-migraine and chronic daily headache

Exclusion criteria

Exclusion criteria: All patients having any neurological morbidity due to any hereditary, trauma, seizure disorder, meningitis, arterio-veinous malformation, stroke, infection, dyselectrolytemia and any possible secondary cause of headache shall be excluded. Pregnancy, liver or kidney failure, malignancy, uncontrolled diabetis and hypertension or headache with underlying psychiatric illness shall be excluded.

Design outcomes

Primary

MeasureTime frame
The primary out come will be defined as 50% decreases in severity and frequency of headache, at each follow-up visitTimepoint: 1 2 and 3 months

Secondary

MeasureTime frame
Effects on habituation viz hearing threshold and brainstem evoked potentials and visual evoked potentials,Timepoint: 1 2 and 3 months

Countries

India

Contacts

Public ContactDr Jayantee Kalita

sgpgims lucknow

jayanteek@yahoo.com8004904630

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026