Effect of decreased body temperature on dose of drugs during cardiac surgery

Effect of hypothermia on dose requirements of cisatracurium or rocuronium during cardiopulmonary bypass

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2018/06/014522

Enrollment

Registered

2018-06-13

Start date

Unknown

Completion date

Unknown

Last updated

2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: I00-I99- Diseases of the circulatory system Health Condition 2: null- PATIENTS POSTED FOR CARDIAC SURGERIES

Interventions

Intervention1: Intravenous administration of muscle relaxant: Either of one muscle relaxant to be given intravenously whenever train of four is more than or equal to one during CPB Control Interventio

Eligibility

Inclusion criteria

Inclusion criteria: Adult patients of either sex posted for cardiac surgeries with moderate hypothermic CPB (28- 32 degree Celsius)

Exclusion criteria

Exclusion criteria: Age 60 YEARS BMI- >30 kg/m2 History of renal, liver or any neuromuscular disorders History of medication interfering with neuromuscular transmission left vebtricular ejection fraction <50 %

Design outcomes

Primary

Measure	Time frame
Duration after which muscle relaxant top up dose required during Cardiopulmonary bypassTimepoint: End of Cardiopulmonary bypass	—

Secondary

Measure	Time frame
Comparision of duration of muscle relaxant top up dose required prebypass, during bypass and post bypassTimepoint: Till end of surgery	—

Countries

India

Contacts

Public ContactGEGAL PRUTHI

SRI JAYADEVA INSTITUTE OF CARDIOVASCULAR SCIENCES AND RESEARCH

parimalapsimha@gmail.com9449611114

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026