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RECUCTION IN PAIN BY PREGABALIN, LIGNOCAINE OR COMBINATION OF BOTH IN RESPONSE TO INJECTION ROCURONIUM GIVEN DURING GENERAL ANAESTHESIA

TO STUDY THE EFFECTS OF PREGABALIN, LIGNOCAINE AND COMBINATION OF PREGABALIN AND LIGNOCAINE IN ROCURONIUM INDUCED PAIN AND WITHDRAWAL - A RANDOMISED CONTROLLED TRIPLE BLIND STUDY

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2018/06/014516
Enrollment
90
Registered
2018-06-12
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- Patients undergoing elective surgeries under general anaesthesia.

Interventions

Intervention1: General Anaesthesia: General Anaesthesia with cuffed endotracheal tube intubation with induction with Inj Propofol and Inj Rocuronium. Control Intervention1: Lignocaine: Lignocaine 40 m

Sponsors

Dr RPGMC Kangra at Tanda
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. ASA class I-II 2. BMI 18.5-29.9 3. Undergoing elective surgeries under general anaesthesia.

Exclusion criteria

Exclusion criteria: 1. Patientâ??s refusal for general anaesthesia 2. Neurological deficits 3. Pregnancy 4.Anticipated difficult intubation or difficult mask ventilation 5. BMI > 30.0 6. Those receiving long analgesics, sedatives, hypnotics, antidepressants 7. Hemodynamic instabilities during induction 8. Patients allergic to study drugs

Design outcomes

Primary

MeasureTime frame
To study the effects of Pregabalin, Lignocaine and combination of Pregabalin and Lignocaine in Rocuronium induced pain and WithdrawalTimepoint: 24 hours—

Secondary

MeasureTime frame
Hemodynamic parameters changesTimepoint: 24 hours;Intensity of pain using NRS during injection Rocuronium in sub-anaesthetic doseTimepoint: 60 seconds;Withdrawal response during injection Rocuronium in intubating doseTimepoint: 60 seconds;Withdrawal response during injection Rocuronium in sub-paralytic doseTimepoint: 60 seconds—

Countries

India

Contacts

Public ContactDr SUDERSHAN KUMAR

Dr. Rajendra Prasad Govt. Medical College, Kangra at Tanda (H.P.)

sudarshan_58@rediffmail.com9418086604

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026