Health Condition 1: null- Patient age 18-60 years of either sex, of ASA grades I and II having BMI less than or equal to 30 kg/m2
Conditions
Interventions
Intervention1: GROUP 2 (Dexmedetomidine): Patients will be given general anaesthesia. This would be followed by administration of inj. fentanyl citrate 1mcg/kg followed by infusion of dexmedetomidine
Sponsors
Vardhman Mahavir Medical College and Safdarjung Hospital
Eligibility
Inclusion criteria
Inclusion criteria: ASA grades I and II, BMI less than or equal to 30 kg/m2
Exclusion criteria
Exclusion criteria: 1. Difficult airway (Mallampati grades 3 & 4 ) 2. Pregnant and nursing women 3. Patients who require emergency surgical interventions. 4. Patients with hemodynamic instability or having cardiac, hepatic, renal, endocrine, hypertensive disorders and on medications like beta-blockers, digitalis, anti-psychotics, anxiolytics, sedatives or patients allergic to study medications.
Design outcomes
Secondary
| Measure | Time frame |
|---|---|
| To assess the level of sedation between the groups using Ramsay Sedation Score.Timepoint: After infusion of test drug | — |
Primary
| Measure | Time frame |
|---|---|
| To compare the hemodynamic responses (HR, NIBP) and SpO2 variations in response to laryngoscopy and endotracheal intubation using either intravenous dexmedetomidine (1mcg/kg) or clonidine (1mcg/kg)Timepoint: At the time of pre-intubation and post-intubation | — |
Countries
India
Contacts
Public ContactDr Mohit Gupta
Vardhman Mahavir Medical College and Safdarjung Hospital
Outcome results
None listed