Health Condition 1: null- Adult ASA physical status I- III patients presenting for elective open abdominal surgery under General Anesthesia at PGIMER.
Conditions
Interventions
Intervention1: Plasmalyte A: Patient received a bolus of 150 ml of study fluid at induction and 2ml/kg/hr + urine output + blood loss every hour. At hypotension fluid challenges were triggered by SPV
Sponsors
Shilpa Joshiya
Eligibility
Inclusion criteria
Inclusion criteria: Adult ASA physical status I-III patients presenting for elective open abdominal surgery under GA at PGIMER, Chandigarh.
Exclusion criteria
Exclusion criteria: Patients with pre-existing renal dysfunction (Sr. creatinine > 1.5mg/dl), those with abnormal sodium, potassium, chloride levels on pre-operative biochemistry screen, resting elevations of PaCO2, known clinical lung disease, H/O congestive heart failure or pulmonary hypertension, pre-operative use of diuretic or steroid replacement therapy, Hb <7gm/dl and those refusing consent were excluded from study participation.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Difference in chloride concentration of less than 3 mEq/L between the plasmalyte and normal saline groups at the end of surgery with restrictive fluid regimen.Timepoint: Difference in chloride concentration of less then 3 mEq/L | — |
Secondary
| Measure | Time frame |
|---|---|
| Acidosis at first post operative day .Timepoint: pH less than 7.35;decreased urine output with restrictive regimen leading to risk of renal injuryTimepoint: urine output less than 0.5ml/kg/hr . risk of renal injury by RIFLE criteria. | — |
Countries
India
Contacts
Public ContactShilpa Joshiya
PGIMER
Outcome results
None listed