Health Condition 1: null- melasma
Conditions
Interventions
Intervention1: dermaroller(1mm needle size) with tranexamic acid (10%): microneedling by dermaroller of 1mm needle size is used as a drug delivery system to apply injection tranexemic acid (10%) topi
Sponsors
Government medical college and hospital Chandigarh
Eligibility
Inclusion criteria
Inclusion criteria: 1. Patients with clinical diagnosis of melasma.
Exclusion criteria
Exclusion criteria: 1. Patients suffering from any significant systemic illness. 2. Patient with known hypersensitivity to tranexamic acid. 3. Patients with any other facial dermatoses. 4. Patients on anticoagulants, oral contraceptive pills, hormone replacement therapy, NSAIDs, antiepileptic medications, isotretinoin or any other phototoxic medication. 5. Pregnancy and lactation. 6. History of thrombotic disease like DVT.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| percentage reduction in Modified MASI (Melasma Area Severity Index) of each half of the face, respose as follow:- No response Minimal or poor response- 0-25% reduction in the modified MASI score Partial or fair response- 26%-50% reduction in the modified MASI score Good response- 51-75% reduction in the modified MASI score Excellent- 75% reduction in the modified MASI score Timepoint: at baseline,2,4 and 8 weeks | — |
Secondary
| Measure | Time frame |
|---|---|
| patient satisfaction score as follows;- excellent-81-100% very good- 61-80% good- 41-60% fair- 21-40% poor-0-20%Timepoint: at baseline,2,4,6 and 8 weeks | — |
Countries
India
Contacts
Public ContactDr Amrit Kaur
Government medical college and hospital, Chandigarh
Outcome results
None listed