Health Condition 1: null- healthy ASA 1 OR 2
Conditions
Interventions
Intervention1: preservative free dexamethasone: preservative free dexamethasone 0.1 mg/kg maximum 4 mg into paravertebral space alone with 0.2% ropivacaine 0.5ml/kg into paravertebral space
Control In
Sponsors
FLUID research grant
Eligibility
Inclusion criteria
Inclusion criteria: All children between 2 and 14 years posted for open pyeloplasty consented/ assented for study
Exclusion criteria
Exclusion criteria: 1. Patients with cutaneous infection at the site of needle puncture, 2. Pathology in the paravertebral space, 3. Allergy to local anesthetic drugs, 4. Obesity, 5. Coagulopathy, 6. Creatinine clearance less than 90 ml//min/1.73m2 7. Kyphoscoliosis 8. Diabetes mellitus 9. Malignancy 10. Psychiatric disorder 11. Immunocompromised child (HIV, already on dexamethasone, inflammatory disease)
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| comparing the efficacy and duration of the paravertebral blockTimepoint: Efficacy of the block will be assessed by calculating total analgesics requirement in both arms in morphine equivalents for 48 hours or till discharge from ward. Duration of the block will be assessed by calculating the time take from block administration to first rescue analgesia administered in minutes. | — |
Secondary
| Measure | Time frame |
|---|---|
| Incidence and severity scores of pains in recovery and surgical ward.FLACC (Face, Legs, Activity, Cry, Consolability) score for preverbal children and VAS(Visual Analogue Scale) score for verbal children.Timepoint: In the recovery ward pain score and rescue analgesia is needed will be noted, at time of arrival and every one hourly till discharge to the surgical ward. In the surgical ward pain score and rescue analgesia is needed will be noted, at the time of arrival and at least every 4th hourly for first 24 hours and at least every 6th hourly till discharge or till 48 hours. ;incidence of adverse events such as vascular puncture (blood aspirate),Abandoned block (unable to place),Failed block (completed but not successful),Respiratory: pneumothorax, respiratory depression, apnea other, Cardiovascular: arrhythmia, hypotension, cardiac arrest, otherTimepoint: within 48 hours from time of block administration or discharge from ward | — |
Countries
India
Contacts
Public ContactAnita Shirley Joselyn
Christian Medical College, Vellore
Outcome results
None listed