A preliminary study is planned to check two different treatment options for the management of infection of the pulp in lower molar teeth.

A preliminary study to evaluate the outcome of combination of non-surgical endodontic and vital pulp therapy for management of mature permanent molar teeth with symptomatic irreversible pulpitis and periapical rarefaction.

Status

Active, not recruiting

Phases

Phase 1

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2018/06/014426

Enrollment

Registered

2018-06-05

Start date

Unknown

Completion date

Unknown

Last updated

2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- Patient with symptomatic irreversible pulpitis and periapical rarefaction in either of roots of mature permanent mandibular molar teeth

Interventions

Intervention1: Combination of non-surgical endodontic and vital pulp therapy: The access to pulp chamber will be gained under local anaesthesia and aseptic conditions. Full pulpotomy (vital pulp thera

Eligibility

Inclusion criteria

Inclusion criteria: 1)Healthy patient of either gender between 18-35 years of age group. 2)Mandibular molar teeth with definitive clinical diagnosis of irreversible pulpitis with periapical involvement (PAI score >= 3) in either of the roots. 3)Positive response to cold and EPT testing. 4)The tooth is restorable. 5)Probing pocket depth and mobility are within normal limits.

Exclusion criteria

Exclusion criteria: 1)Teeth with definitive clinical diagnosis of Irreversible Pulpitis which are not associated with periapical rarefaction. Intraoperative exclusion criteria: 1)Bleeding cannot be controlled within 6 mins with pressure pack. 2)Clinical diagnosis changes from symptomatic irreversible pulpitis to pulp necrosis.

Design outcomes

Primary

Measure	Time frame
To compare the clinical and radiographic periapical healing in mature permanent molar teeth with symptomatic irreversible pulpitis and periapical rarefaction after the following treatment procedures: a.Non-surgical endodontic therapy b.Combination of non-surgical endodontic and vital pulp therapy Timepoint: 6 months, 12 months	—

Secondary

Measure	Time frame
No secondary outcome measurementTimepoint: Not applicable	—

Countries

India

Contacts

Public ContactAmrita Chawla

Centre for Dental Education and Research, AIIMS, New Delhi

dr.amritachawla@gmail.com9871445522

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026