Health Condition 1: null- Patients suffering from laryngeal cancer
Conditions
Interventions
Intervention1: PMMF ARM: All previously treated patients of larynx and hypopharynx carcinoma with biopsy proven recurrence / residual disease, suitable for salvage total laryngectomy and primary closu
Sponsors
Tata memorial hospital
Eligibility
Inclusion criteria
Inclusion criteria: 1-Recurrent / residual lesions irrespective of histology of larynx and hypopharynx previously treated with radiotherapy/ chemoradiotherapy undergoing salvage total laryngectomy. 2-Patients in whom primary pharyngeal closure is possible with no need for pharyngeal reconstruction to augment pharyngeal mucosa closure. 3- Patients with age between 18 years -70 years 4- Patients with dysfunctional larynx as deemed by the tumor board decision with negative histopathology report. Dysfunctional larynx may include: persistent tracheostomy, chondronecrosis, persistent nasogastric tube use, and aspiration
Exclusion criteria
Exclusion criteria: 1-Treatment naive patient with no prior radiotherapy/chemo-radiotherapy. 2-Patients suitable for conservation laryngeal surgery. 3-Patients requiring pharyngeal reconstruction for pharyngeal mucosa closure in whom primary pharyngeal closure not possible.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To assess the utility of pectoralis major myofascial flap in reducing pharyngocutaneous fistula rates after salvage total laryngectomy.Timepoint: At the end of completion of treatment | — |
Secondary
| Measure | Time frame |
|---|---|
| To identify factors affecting pharyngocutaneous fistula in salvage total laryngectomy.Timepoint: At the end of completion of treatment | — |
Countries
India
Contacts
Public ContactDr. Gouri Pantvaidya
Tata Memorial Hospital
Outcome results
None listed