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BEST DOSE AMONG THE THREE

COMPARATIVE EFFICACY OF THREE DIFFERENT DOSES OF INTRANASAL DEXMEDETOMEDINE FOR PREMEDICATION IN CHILDREN

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2018/05/014305
Enrollment
60
Registered
2018-05-31
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- CHILDREN OF AGE 1-6 YRS,ASA GRADE ONE AND TWO UNDERGOING GENERAL ANESTHESIA Health Condition 2: H00-H59- Diseases of the eye and adnexa

Interventions

Intervention1: Dexmedetomedine: Comparing efficacy of three different doses of intranasal dexmedetomedine-0.5microgram/kg, 1microgm/kg , 1.5microgm/kg in children 1-6 yrs of age for anxiolysis and eff

Sponsors

INSTITUTIONAL
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: AGE 1-6 YRS ASA GRADE ONE AND TWO PATIENT UNDERGOING GENERAL ANESTHESIA

Exclusion criteria

Exclusion criteria: KNOWN ALLERGY OR HYPER SENSITIVITY TO DEXMEDETOMEDINE. ABERRANT NASAL ANATOMY. ACUTE OR CHRONIC NASAL TRAUMA THAT MAY PRECLUDE ADEQUATE INTRANASAL DELIVERY OF DRUG. ANTICIPATED DIFFICULT AIRWAY. LIVER DYSFUNCTION. CARDIAC ARRHYTHMIAS, CONGENITAL HEART DISEASE ,MENTL RETARDATION.

Design outcomes

Primary

MeasureTime frame
TO EVALUATE AND COMPARE EFFICACY OF THREE DIFFERENT DOSES OF INTRANASAL(ROUTE) DEXMEDETOMEDINE FOR PREMEDICATION IN CHILDREN FOR PREOPERATIVE ANXIETY USING THE mYPAS SCALE TAKING ONE BASELINE THEN AFTER ,30MIN,45MIN,JUST AFTER TAKING IN OPERATION THEATRETimepoint: TO EVALUATE AND COMPARE EFFICACY OF THREE DIFFERENT DOSES OF INTRANASAL DEXMEDETOMEDINE FOR PREMEDICATION IN CHILDREN FOR PREOPERATIVE ANXIETY USING THE mYPAS SCALEEFFICACY OF THREE DIFFERENT DOSES OF INTRANASAL(ROUTE) DEXMEDETOMEDINE FOR PREMEDICATION IN CHILDREN FOR PREOPERATIVE ANXIETY USING THE mYPAS SCALE TAKING ONE AT BASELINE THEN AFTER ,30MIN,45MIN,JUST AFTER TAKING IN OPERATION THEATRE—

Secondary

MeasureTime frame
1-INDUCTION COMPLIANCE USING INDUCTION COMPLIANCE CHECKLIST. 2-HEMODYNAMIC RESPONSES TO DEFINITIVE AIRWAY INSERTIONTimepoint: HEART RATE,SYSTOLIC BLOOD PRESSURE,DIASTOLIC BLOOD PRESSURE,MEAN ARTERIAL BLOOD PRESSURE WILL BE RECORDED AT IMMEDIATELY BEFORE AND 1,3,5,7,10MINS TO DEFINITIVE AIRWAY INSERTION.—

Countries

India

Contacts

Public ContactKULDEEP SINGH

MAULANA AZAD MEDICAL COLLEGE

nprasadgovil@yahoo.com9968604372

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026