Health Condition 1: H401- Open-angle glaucoma Health Condition 2: H402- Primary angle-closure glaucoma
Conditions
Interventions
Intervention1: NIL: NIL
Intervention2: Glaucoma filteration surgey: Surgical method for reducing intraocular pressure in advanced glaucoma patients who are unresponsive to maximum medical therapy for
Sponsors
Postgraduate Institute of Medical Education and Research
Eligibility
Inclusion criteria
Inclusion criteria: Primary open angle glaucoma patients (POAG) Primary angle closure glaucoma patients (PACG)
Exclusion criteria
Exclusion criteria: (i)Extremes of ages (age less than 40 years and more than 65 years) (ii) Eyes with ocular diseases other than cataract and/or POAG,PACG (iii) Eyes that underwent cataract surgery (and implantation of an intraocular lens) within 6 months prior to aqueous humour collection (to exclude the effect of postoperative in�ammation following cataract surgery) (iv) Glaucoma due to secondary causes.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Cytokines TFG-beta ,TNF-alpha ,IFN-gamma ,IL-6,MCP-1,IL10,IFN-alpha levels in tearfilm and aqueous humor with the IOP trend and bleb morphologyTimepoint: preoperative day, postoperative day 1,7,14,21,28,42,90 tearfilm and aqueous humor samples intraoperatively | — |
Secondary
| Measure | Time frame |
|---|---|
| Requirement of antiglaucoma medication Timepoint: at 3 months follow up after surgery | — |
Countries
India
Contacts
Public ContactSurinder Singh Pandav
Postgraduate Institute of Medical Education and Research
Outcome results
None listed