chloride resticted fluid versus chloride liberal fluid in management of dengue shock in children

chloride restrictive versus chloride liberal fluid therapy protocol in children aged 2 months-18 years with dengue shock-open label randomised control study

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2018/05/014256

Enrollment

Registered

2018-05-31

Start date

Unknown

Completion date

Unknown

Last updated

2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- children with dengue shock requiring intravenous fluid therapy

Interventions

Intervention1: chloride restricted fluid(plasmalyte): dose:10-20ml/kg fluid bolus route:intravenous Control Intervention1: chloride liberal fluid(normal saline): dose:10-20ml/kg fluid boluses till sho

Eligibility

Inclusion criteria

Inclusion criteria: children with dengue shock

Exclusion criteria

Exclusion criteria: Children with primary immunodeficiency or dependant on blood transfusion or known case of chronic liver disease

Design outcomes

Primary

Measure	Time frame
delta sodium,delta potassium,delta chloride,delta biarbonate,urine output trendTimepoint: every 12 hours till child stops receiving study fluids	—

Secondary

Measure	Time frame
ejection fraction in echo,E/Avalue in echoTimepoint: till intravenous fluid therapy is on flow	—

Countries

India

Contacts

Public ContactDrKSasidharan

Dr Mehta Hospital

sasidarpgi@gmail.com9940587408

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026