To know the different level of bone destrusting molecule level in fulid inside the gums after treating gum disease with and with out the use of LASER

COMPARATIVE EVALUATION OF SCLEROSTIN LEVELS IN GINGIVAL CREVICULAR FLUID IN THE TREATMENT OF CHRONIC PERIODONTITIS PATIENTS USING DIODE LASER AS AN ADJUNCT TO SCALING AND ROOT PLANING- A CLINICO-BIOCHEMICAL STUDY

Status

Recruiting

Phases

Phase 3Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2018/05/014253

Enrollment

Registered

2018-05-30

Start date

Unknown

Completion date

Unknown

Last updated

2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- chronic periodontitis patients with periodontal pocket depth more than 5mm

Interventions

Intervention1: scaling and root planing: scaling and root planing will be done only once at baseline,ie.1st day. sclerostin level in gingival crevicular fluid will be checked at baseline and 90th day.

Eligibility

Inclusion criteria

Inclusion criteria: Inclusion Criteria 1. Patient diagnosed with chronic periodontitis and good systemic health 2. Untreated chronic periodontitis 3. Patients with minimum of 20 number of teeth excluding third molar, with pocket depth more than or equal to 5mm 4. Patients ranging from 35-55 years of age 5. Patients willing to participate in the study

Exclusion criteria

Exclusion criteria: Exclusion Criteria 1.Patients with systemic diseases (e.g., diabetes mellitus; cancer; human immunodeficiency virus; bone-related diseases that compromise sclerostin, OPG, or RANKL levels: osteoporosis; and collagen-metabolic diseases or disorders) 2. Pregnant and lactating women. 3. Smoking within the past 5 years. 4. Patients not willing for surgery

Design outcomes

Primary

Measure	Time frame
1.sclerostin level in gingival crevicular fluid 2.Gingival index: (Loe & Sillness 1963) 3.Bleeding index(Muhlemann & son 1971) 4.Probing pocket depth 5.Clinical attachment levelTimepoint: day1 day90	—

Secondary

Measure	Time frame
1.Gingival index: (Loe & Sillness 1963) 2.Bleeding index(Muhlemann & son 1971) 3.Probing pocket depth 4.Clinical attachment levelTimepoint: day1,day7,day30,day90	—

Countries

India

Contacts

Public ContactNITHYA R KRISHNAN

Coorg institute of dental sciences

bsjpai@gmail.com9448163710

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026