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ââ?¬Å?USE OF DEXMEDETOMIDINE TO AVOID CHANGES IN PULSE AND BLOOD PRESSURE DUE TO REMOVAL OF ENDOTRACHEAL TUBE IN PATIENTS UNDERGOING SURGERY UNDER GENERAL ANAESTHESIAââ?¬â?? PROSPECTIVE, RANDOMIZED STUDY.ââ?¬?

ââ?¬Å?DEXMEDETOMIDINE FOR THE PREVENTION OF HAEMODYNAMIC RESPONSE TO EXTUBATION IN PATIENTS UNDERGOING SURGERY UNDER GENERAL ANAESTHESIAââ?¬â?? PROSPECTIVE, RANDOMIZED STUDY.ââ?¬?

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2018/05/014228
Enrollment
150
Registered
2018-05-30
Start date
Unknown
Completion date
Unknown
Last updated
2022-10-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- ASA GRADE I & II Health Condition 2: O- Medical and Surgical

Interventions

Intervention1: 1.IV IV DEXMEDETOMIDINE 0.25 MCG/KG OVER 10 MINUTES PRIOR TO EXTUBATION 2.IV DEXMEDETOMIDINE 0.5 MCG/KG OVER 10 MINUTES PRIOR TO EXTUBATION 3.IV NORMAL SALINE 20CC OVER 10 MINUTES PRI

Sponsors

INDRAPRASTHA APOLLO HOSPITAL NEW DELHI
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. Age 18 ââ?¬â?? 65yrs 2. Either sex. 3. Elective cases undergoing abdominal surgeries lasting more than one hour. 4. ASA I & ASA II.

Exclusion criteria

Exclusion criteria: 1. Patientââ?¬•s refusal to take part in our study. 2. Patient on beta blockers or alpha blockers. 3. Patient requiring epidurals for post-operative pain relief. 4. Pregnant women. 5. Patients with BMI more than 33, those with history of drug abuse or psychological disorder and obese patients, with difficult airway or history of sleep apnoea. 6. Age 65 years.

Design outcomes

Primary

MeasureTime frame
1.Prevention of rise in blood pressure and heart rate by more than 15% of baseline after injection of Dexmedetomidine 0.50 micro gram per Kg body weight 10 minutes prior to extubation. 2.Prevention of rise in blood pressure and heart rate by more than 15% of baseline after injection of Dexmedetomidine 0.25 micro gram per Kg body weight 10 minutes prior to extubation.Timepoint: 2 hour

Secondary

MeasureTime frame
EXTUBATION TIME SEDATION SCORE Timepoint: 2 hour

Countries

India

Contacts

Public ContactDr SANJEEV ANEJA

INDRAPRASTHA APOLLO HOSPITAL DELHI

Rvj4me@gmail.com9810511510

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026