Comparison of injection of steroid vs hypertonic dextrose in knee for pain relief in patients of knee arthritis

A comparitive study of intraarticular injection of steroid vs prolotherapy for pain relief in patients of osteoarthritis knee

Status

Recruiting

Phases

Phase 2

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2018/05/014227

Enrollment

Registered

2018-05-30

Start date

Unknown

Completion date

Unknown

Last updated

2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- Patients with osteoarthritis knee grade I, II and III

Interventions

Intervention1: Triamcinolone acetonide: Dose 40mg with 1 ml plain lignocaine at 0, 1 and 2 months intraartcularly in knee joint Intervention2: 25% Dextrose: 8 ml of 25% dextrose intraarticularly at 0,

Eligibility

Inclusion criteria

Inclusion criteria: Knee osteoarthritis grade I, II and III Patients with VAS > 5 Platelet count < 1.5 lakh

Exclusion criteria

Exclusion criteria: Patients giving negative consent. Inflammatory arthritis. History of recent surgery or intraarticular injection of steroid or hyaluronic acid in last 3 months. Patients on active anticoagulant therapy. Liver or haematological/coagulation disorders. Active local site infection/malignancy

Design outcomes

Primary

Measure	Time frame
VAS score for pain assessment Quality of life by Mc gill questionarre, dose of rescue analgesia, repetition of doses of rescue analgesiaTimepoint: At 0, 1 week, 1, 2, 3, 4, 5, 6 months	—

Secondary

Measure	Time frame
NoneTimepoint: Not applicable	—

Countries

India

Contacts

Public ContactShashank Kumar

KGMU

saritacsmmu@rediffmail.com8318120314

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026