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Comparison of Healing and Bone Formation with PRF alone and PRF with Ornidazole after Removing Lower Last Molar by Surgical Procedure

â??A Comparative Controlled Clinical Evaluation of Soft Tissue Healing and Bone Regeneration with Platelet Rich Fibrin and Ornidazole after Surgical Removal of Lower 3rd Molars.â??

Status
Active, not recruiting
Phases
Phase 3Phase 4
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2018/05/014221
Enrollment
20
Registered
2018-05-30
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- MESIO-ANGULARLY IMPACTED BILATERAL LOWER 3RD MOLAR

Interventions

Intervention1: PRF (PLATELET RICH FIBRIN) WITH 1mg Ornidazole powder : INTO THE SOCKET AFTER SURGICAL REMOVAL OF LOWER 3RD MOLAR (TEST SIDE) Control Intervention1: PRF ALONE: INTO THE SOCKET AFTER SUR

Sponsors

SRI HASANAMBA DENTAL COLLEGE AND HOSPITAL
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Patients having bilateral mesio-angularly impacted third molars of type Class I and Position A and fulfilling ASA-1 criteria

Exclusion criteria

Exclusion criteria: Patients in whom surgery is medically contraindicated. Patients with mandibular second molar/molars missing or partially erupted. Immuno-compromised patients and patients with metabolic disorders. Patients on long term steroid therapy. Patients allergic to the nitro-imidazole drug group. Patients with active infection pre-operatively. Patients with alcohol abuse habits.

Design outcomes

Primary

MeasureTime frame
BOTH PRF ALONE AND PRF WITH ORNIDAZOLE SHOWED ADEQUATE SOFT TISSUE HEALING HOWEVER IMPROVED HEALING WITH LESS POST-OP DISCOMFORT WAS NOTED IN PRF INFUSED WITH ORNIDAZOLETimepoint: 7 DAYS

Secondary

MeasureTime frame
RAPID AND SLIGHTLY BETTER BONE HEALING WAS SEEN WHEN PRF GEL WAS INFUSED WITH ANTIBIOTICSTimepoint: 3 MONTHS

Countries

India

Contacts

Public ContactDR GARIMA SACHDEVA

SRI HASANAMBA DENTAL COLLEGE AND HOSPITAL

manjunath_kurki@yahoo.in9743779536

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026