Can Ringer Lactate Used As Perfusion Fluid In Live Donor Renal Transplant?

Histidine-Tryptophan-Ketoglutarate Solution V/s Ringer Lactate As Perfusion Fluid In Renal Transplant: A RANDOMISED TRIAL

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2018/05/014211

Enrollment

Registered

2018-05-29

Start date

Unknown

Completion date

Unknown

Last updated

2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: N186- End stage renal disease

Interventions

Intervention1: RINGER LACTATE: Ringer lactate solution is the most physiological fluid as its electrolyte content is nearly similar to the free concentration of plasma. Ringer lactate is a solution th

Eligibility

Inclusion criteria

Inclusion criteria: Undergoing renal transplant after giving consent for the study

Exclusion criteria

Exclusion criteria: 1 Complex vascular anatomy requiring prolonged bench reconstruction estimated > 3 hours 2 Cadaveric transplant 3 Repeat implantation 4 Non adherence with study protocol 5 Myocardial infarction within the last 6 months or active Myocardial Ischaemia 6 Transient ischemic attack or stroke within the last 6 months 7 Severe restrictive or obstructive pulmonary disease

Design outcomes

Primary

Measure	Time frame
To perform a randomised comparison of Histidine-Tryptophan-Ketoglutarate and Ringer Lactate solution as non pulsatile perfusion for live donor renal transplantation in term of graft function in 1 month follow up with measures of serum creatinine, serum cystatin C, plasma malondialdehyde and rejection episodesTimepoint: 1 MONTH FOLLOW UP	—

Secondary

Measure	Time frame
NILTimepoint: NIL	—

Countries

India

Contacts

Public ContactAMBUJ AGARWAL

RENAL TRANSPLANT SURGERY, PGIMER

deepesh.doc@gmail.com9417434184

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026