Health Condition 1: null- Bronchial Asthma
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. All (old or new) diagnosed patients of bronchial asthma (age group 18-55 years of either sex who will be started on inhaled corticosteroids (ICS) for the next 4 weeks according to GINA (global initiative for asthma) guidelines (standard treatment of care) coming to a medicine unit of Smt. Sucheta Kriplani Hospital, New DelhI (Out patient department/ In patient department) will be included. For Healthy Volunteers: 1. Attendants of the patients who are not having any known illness and are not on any type medication will be included with their consent. Further, any healthy person who is willing to participate will also be included.
Exclusion criteria
Exclusion criteria: 1. Patients who have taken corticosteroids in any form in last 4 weeks 2. Patient with any other co-existent and active pulmonary infection 3. Imminent respiratory arrest as indicated by- a.Drowsy/confused patient b.Paradoxical thoraco-abdominal movements with respiration c.Absent wheeze d.Bradycardia (pulse 4. Evidence of active infection on chest X-ray 5. Pregnancy 6. Clinical evidence of any connective tissue disorders 7. Unwillingness to give consent.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Comparison of levels of periostin in healthy adults with asthmatic patients. Change in serum levels of periostin in asthmatic patients on treatment with inhaled corticosteroids. Timepoint: 4 weeks | — |
Secondary
| Measure | Time frame |
|---|---|
| Correlation between asthma severity score as measured by SOA questionnaire and periostin level. Change in quality of life scores in asthma as measured by QOLtech AQLQ questionnaire, after treatment with inhaled corticosteroids Timepoint: 4 weeks | — |
Countries
India
Contacts
Lady Hardinge Medical College