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Reversal of Muscle paralysis based on the amount of residual weakness .

Reversal of Neuromuscular Blockade based on Train-of-four (TOF) response.

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2018/05/014182
Enrollment
150
Registered
2018-05-29
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K802- Calculus of gallbladder without cholecystitis Health Condition 2: H661- Chronic tubotympanic suppurative otitis media Health Condition 3: N830- Follicular cyst of ovary Health Condition 4: null- patients(20-60 years), undergoing any surgery lasting for more than one hour under general anaesthesia with endotracheal tube.

Interventions

Intervention1: reversal of neuromuscular blockade based on train-of-four ratio: any person undergoing surgery under general anaesthesia ,requires muscle relaxants.Relaxant used is vecuronium ....intra

Sponsors

Kasturba Medical College Manipal
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: ASA Physical Status 1 or 2 weight (BMI any surgery requiring general anaesthesia with endotracheal tube lasting for more than one hour

Exclusion criteria

Exclusion criteria: neuromuscular disorders neurological impairments obese (BMI >30) Pregnant women renal dysfunction( creatinine >1.8) hepatic dysfunction(LFT >50% of normal values) drugs interfering with neuromuscular transmission

Design outcomes

Primary

MeasureTime frame
signs of residual muscle weakness in the post operative periodTimepoint: after extubation and shifting the patient to post operative ward

Secondary

MeasureTime frame
1. signs of residual muscle weakness 2. any complications of reversal agent Timepoint: after extubation in the post operative period within 24 hrs;1. TOF ratio at the time of giving reversal agent 2. time taken for extubation after giving reversal 3. TOF ratio at the time of extubation Timepoint: before extubation .

Countries

India

Contacts

Public ContactSPURTI KALBURGI

Kasturba Medical College , Manipal

hm.krishna@manipal.edu9448983314

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026