Health Condition 1: null- Awaited for abdominal hysterectomy operation
Conditions
Interventions
Intervention1: Bupivacaine with Fentanyl (Local anaesthetic and opioid): A single dose 0.5% Bupivacaine with 100microgram Fentanyl drugs by route of administration epidural injection
Total duration fo
Sponsors
Institute of Postgraduate Medical Education Research
Eligibility
Inclusion criteria
Inclusion criteria: 1. Adult female patients, aged between 30 to 65 yrs 2. BMI 18.5 to 29.9 kg/meter2 3. ASA physical status I & II. 4. Patients scheduled for elective abdominal hysterectomy under lumbar epidural anaesthesia.
Exclusion criteria
Exclusion criteria: a) Patient refusal. b) Any contraindication to epidural anaesthesia â?? i. Infection at the site of injection ii. Coagulopathy iii. Neurological disorders and psychiatric disorder iv. Haemodynamically compromised patients v. Sepsis vi. Gross anatomical abnormality of vertebral column. vii. Known allergy to either bupivacaine or ropivacaine or fentanyl. viii. Patients on chronic antiplatelet drugs and anticoagulants.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To conclude that in the present study using 0.5% bupivacaine with fentanyl and 0.75% ropivacaine with fentanyl epidurally, ropivacaine produced an earlier onset but similar duration of sensory block. The onset, quality and duration of motor block were comparable in both the groups.Timepoint: During hysterectomy operation for two hours | — |
Secondary
| Measure | Time frame |
|---|---|
| In hemodynamics, heart rate was comparable in both groups but blood pressures (SBP, MAP, DBP) was decrease significantly in bupivacaine group after 20min of administration of the epidural study drug.Timepoint: Post operative assessment for 24hours | — |
Countries
India
Contacts
Public ContactDR OINDRILA SINHA
IPGMER, Kolkata
Outcome results
None listed