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A cross sectional study to see the prevalence of derangement in metabolic parameters with anti-epileptic drugs in adult patients of generalized tonic clonic seizures and its impact on health related quality of life

Metabolic Parameters & Health Related Quality of Life with Anti-Epileptic Drugs in Adult Patients of Generalized Epilepsy: A Cross Sectional Study

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2018/05/014125
Enrollment
160
Registered
2018-05-25
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- patients suffering from generaalized tonic clonic epilepsy stabilized on anti epileptic drugs for atleast 3 months

Interventions

None listed

Sponsors

Pt B D Sharma Post graduate institute of medical sciences
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1)Patient 18 - 65 years of age of either gender. 2)Patient of generalized epilepsy on stable antiepileptic drugs (monotherapy or combination) for at least 3 months. 3)Patients receiving antiepileptic monotherapy or combination (commercial preparations of same brand). 4)Patient willing to provide written informed consent.

Exclusion criteria

Exclusion criteria: 1)Patients with psychogenic/ non epileptic seizures (NES) 2)Patient having history of any focal pathology/ lesions of brain 3)Patient with co-existing Type 2 Diabetes mellitus 4)Patient with dyslipidaemia who are already on lipid lowering agents. 5)Patient on medication that are known to interfere with body weight status, such as antidepressants, corticosteroids and anti-thyroid drugs. 6)Pregnant patients of epilepsy. 7)Patients with history of alcohol/ substance abuse 8)Patient having any personality or psychiatric disorders.

Design outcomes

Primary

MeasureTime frame
metabolc parameters with anti epileptic drugs and its association with quality of lifeTimepoint: At the end of study period. Cross sectional so single time point considered

Secondary

MeasureTime frame
physical activity and BMI with with anti epileptic drugsTimepoint: At the end of study period. Cross sectional so single time point considered

Countries

India

Contacts

Public ContactHimanshu Gupta

Pt B D Sharma PGIMS/UHS, Rohtak

savita_verma@hotmail.com

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026