Skip to content

The effect of using drug(mannitol) in additional quantities according to weight in patient undergoing open heart surgery.

"Efficiency of using mannitol according to weight in patients undergoing cardiopulmonary bypass".

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2018/05/014115
Enrollment
60
Registered
2018-05-25
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- patients with Heart diseases requiring open heart surgeries admitted through out patient department in clinically stable condition

Interventions

Intervention1: efficiency of using mannitol according to weight in patients undergoing CPB: 1gm/kg body weight with mild hypothermia (nasopharyngeal temperature � 32 °C during CPB)
duration of therapy- 1 day. Control Intervention1: efficiency of using mannitol according to weight in patients undergoing CPB: 1.5gm/kg body weight with mild hypothermia (nasopharyngeal temperature â

Sponsors

Director ALL INDIA INSTITUTE OF MEDICAL SCIENCES
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Patients were equally randomized into two groups: Group 1, 1gm/kg body weight with mild hypothermia (nasopharyngeal temperature >= 32 °C during CPB); Group 2, 1.5gm/kg body weight with mild hypothermia (nasopharyngeal temperature >= 32 °C during CPB). The same surgeon performed all operations.

Exclusion criteria

Exclusion criteria: Respiratory insufficiency with need of respiratory support, Kidney failure Liver failure and Neurological impairment Patients Patient whose age > 75 years Weight < 50

Design outcomes

Primary

MeasureTime frame
To determine whether the 2 types of mannitol doses in determining the renal function test.Timepoint: 24hrs

Secondary

MeasureTime frame
To determine whether the 2 types of mannitol doses in determining the urine output.Timepoint: 24hrs

Countries

India

Contacts

Public ContactM SHIVA ANIL VARMA

AIIMS,New Delhi

sachintalwar@hotmail.com9868398136

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026