Health Condition 1: null- Male type baldness
Conditions
Interventions
Intervention1: Platelet Rich Plasma: subcutaneous injection of platelet rich plasma monthly for three sitting over whole scalp followed by 3 month follow up
platelet rich plasma prepared from patient
Sponsors
Institute of Medical sciences Banaras Hindu University
Dr Tulika Rai
Eligibility
Inclusion criteria
Inclusion criteria: 1. All the patients not using topical minoxidil and finasteride for at least 6 months will be considered for PRP therapy. 2. Age group 20 â?? 60 years 3. Sex- Male 4. Mild to moderate AGA (Hamilton-Norwood score II-V) . 5. Patients willing to come for follow up every month for 5 months.
Exclusion criteria
Exclusion criteria: 1. Patients not giving informed written consent, unable to understand the protocol and uncooperative patients. 2. Any inflammation, erythema or scarring over scalp except mild seborrheic dermatitis. 3. Patients who have history of malignancies, platelets disorders or bleeding disorders, anemia ( haemoglobulin of less than 10 gm/dl), bone marrow aplasia, diabetes, sepsis, and cancer. 4. Patients taking theses any of these medications- i. Anti-coagulants â?? heparin, warfarin ii. Anti-hypertensives â?? beta-blockers, ACE inhibitors hormones iii. Anticonvulsants â?? valproic acid, carbamazepine, phenytoin, mood stabilizers Antidepressants, lithium iv. Aspirin or any non-steroidal anti-inflammatory drugs two week prior to procedure. v. Other medications cimetidine, retinoids (acitretin > isotretinoin), antithyroid drugs, cholesterol lowering drugs, interferons, amphetamines, bromocriptine, levodopa, some antipsychotic and anti-anxiety drugs, rarely tricyclic antidepressants such as amitriptyline 5. Patients who are known to be HIV, hepatitis B or C positive or otherwise immunocompromised. 6. Patients with a propensity for keloids 7. Patients on antiplatelet drugs like aspirin or non-steroidal anti-inflammatory drugs.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Hair density Hamilton Norwood grading Patient self assessmentTimepoint: every month for 5 months | — |
Secondary
| Measure | Time frame |
|---|---|
| Age sex occupation Education status Family History History of previous treatment for male type baldness Effect on personality Timepoint: Every month for 5 months | — |
Countries
India
Contacts
Public ContactDr Vijay Kumar
Institute of Medical Sciences BHU
Outcome results
None listed