None listed
Conditions
Interventions
Intervention1: 3 groups: Aerobic exercise, resistance exercise and combination of both
for 3 months
Control Intervention1: nil: nil
Sponsors
Dr Pranathi R
Eligibility
Inclusion criteria
Inclusion criteria: BMI:18.5-30kg/m2 Impaired oral glucose tolerance test and fasting plasma glucose(prediabetes: FBS 101-125mg/dl, PPBS 141-199 mg/dl, HbA1c 5.7-6.4%) Normal oral glucose tolerance test and fasting plasma glucose(controls: FBS <100 mg/dl, PPBS <140 mg/dl, HbA1C <5.7%)
Exclusion criteria
Exclusion criteria: 1. Presence of chronic diseases (i.e., hypertension, tuberculosis, cancer, chronic renal failure, ischemic heart disease etc.,) 2. Any form of anemia 3. Any form of peripheral neuropathy 4. Muscular dystrophies 5. Any form of joint injuries or surgeries (knee and wrist) 6. History of osteoarthritis 7. Weight loss greater than 2 Kg in the past 6 months 8. Physical activity level > 1.75 9. Any history of chronic alcohol intake or tobacco consumption including cigarettes 10. Retinopathy 11. Any form of surgeries
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Glycated hemoglobinTimepoint: baseline and after 12 weeks intervention | — |
Secondary
| Measure | Time frame |
|---|---|
| Insulin sensitivity and beta cell functions, Muscle quality, Body composition, mRNAs of intracellular signaling pathway Timepoint: baseline and after 12 weeks intervention | — |
Countries
India
Contacts
Public ContactDr Pranathi Racha
St Johns Medical College
Outcome results
None listed