Health Condition 1: null- PATIENTS UNDERGOING CPB ON PUMP HEART SURGERY
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: To determine femoral and radial arterial pressure difference before, during and after cardiopulmonary bypass and to calculate the bias and limits of agreement during various phases of the surgery 1. To determine whether the bias is correlated with a) Use of intravenous vasoactive agents b) Systemic vascular resistance
Exclusion criteria
Exclusion criteria: Patients who are on pre operative intravenous vasoactive drugs, such as inotropes and vasodilators and patients requiring Intra Aortic Balloon Pump (IABP) support will be excluded from the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| There was no significant femoro-radial gradient in the systolic, mean or diastolic pressure before, during or after CPB. What small bias there was, was not correlated with either cardiac output or systemic vascular resisatance. Administration of vasoconstrictor drugs reduced the femoro-radial gradient. We conclude that there is no significant femoro-radial gradient in adult patients undergoing cardiac surgery under CPB, when appropriately sized arterial cannulas are used. Timepoint: Intra operative 3 to 5.5hours | — |
Secondary
| Measure | Time frame |
|---|---|
| We did not find any significant femoro-radial gradient (bias) in either systolic, mean or diastolic pressure at any phase during the surgery. We also did not see any correlation of bias with SVR.Timepoint: Intra operative 3 to 5.5hours | — |
Countries
India
Contacts
PGIMER, Chandigarh