Comparison Of Palonosetron And Palonosetron And Dexamethasone For Preventing Post Operative Nausea And Vomiting In Patients Undergoing Middle Ear Surgeries.

A Comparative Study Of Palonosetron Versus Palonosetron And Dexamethasone For Prevention Of Post Operative Nausea And Vomiting In Patients Undergoing Middle Ear Surgery.A Prospective Randomized Double-Blind Study

Status

Active, not recruiting

Phases

Phase 3Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2018/05/014063

Enrollment

100

Registered

2018-05-23

Start date

Unknown

Completion date

Unknown

Last updated

2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- ASA-1 And 2

Interventions

Intervention1: Palonosetron And Dexamethasone: Patients Will Be Given Iv 0.075 Mg Palonosetron And 4 Mg Dexamethasone And asked for nausea and vomiting and any side effects at 0-6 hrs, 12-24 hrs,24-36

Eligibility

Inclusion criteria

Inclusion criteria: Patients With ASA-1 And 2 Scheduled For Elective Middle Ear Surgeries Willing To Give Written And Informed Consent

Exclusion criteria

Exclusion criteria: Patients With History Of Smoking History Of Drug Or Alcohol Abuse Patients With Impaired Kidney Or Liver Function Patients Who Had Recieved Anti-Emetics Within 24 hrs Before Scheduled Surgery,Mensturating,Pregnant Or Lactating Women patients who had history of motion sickness and history of previous post-operative nausea and vomiting known allergy to study drug

Design outcomes

Primary

Measure	Time frame
Post operative nausea and vomiting, retching,other side effects will be asked forTimepoint: 0-6hrs, 6-12hrs,12-24hrs,24-36hrs and 36-48 hrs	—

Secondary

Measure	Time frame
Post operative nausea and vomiting, retching,other side effects will be asked forTimepoint: 0-6hrs, 6-12hrs,12-24hrs,24-36hrs and 36-48 hrs	—

Countries

India

Contacts

Public Contactkanhaiya kumar

Igims

drraj76pmch@gmail.com7783865337

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026