An observational study to find effect of high osmolarity fluid addition in heart-lung bypass machine circuit on extra water which accumulates outside lungs in adult patients undergoing CORONARY ARTERY BYPASS GRAFT SURGERY.

A COMPARATIVE OBSERVATIONAL STUDY TO EVALUATE EFFECT OF HYPERONCOTIC CARDIO-PULMONARY BYPASS PRIMING ON EXTRAVSACULAR LUNG WATER IN ADULT PATIENTS UNDERGOING CORONARY ARTERY BYPASS GRAFT SURGERY.

Status

Active, not recruiting

Phases

Phase 4

Study type

Observational

Source

CTRI

Registry ID

CTRI/2018/05/014025

Enrollment

Registered

2018-05-21

Start date

Unknown

Completion date

Unknown

Last updated

2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- Coronary artery bypass graft surgery

Interventions

Intervention1: Hexa ethyl starch6% (HES 6%): HES 6% dosage 20-30ml/kg for 24 hours.Used for hyperoncotic priming of CPB circuit in adult patients undergoing CABG Control Intervention1: Ringers Lactate

Eligibility

Inclusion criteria

Inclusion criteria: patient undergoing coronary artery bypass graft surgery

Exclusion criteria

Exclusion criteria: redo CABG patients, weight <40kg, emergency cases, patients on ECMO support, impaired renal function, patient with low left ventricular ejection fraction

Design outcomes

Primary

Measure	Time frame
Intra/perioperative observation of â?? pH, pO2, pCO2, K+, Na+, Ca2+, Hct/Hb, urine output, lactate, ABG report,extravascular lung water etc. Timepoint: peri and intra operatively (after cross clamp on and off)	—

Secondary

Measure	Time frame
post-operatively observation of- EVLW, MAP, cardiac and pulmonary functions, icu stay etc. Timepoint: postoperatively, after 6,12 and 24hrs in ICU	—

Countries

India

Contacts

Public ContactShalu Chaudhary

AIIMS

sachintalwar@hotmail.com9868398136

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026