A clinical trial to study the effect of two different radiotherapy treatment techniques in patients with cancer cervix

A randomised study to evaluate the acute toxicity in patients of locally advanced cervical cancer treated with 3DCRT versus IG-VMAT

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2018/05/014021

Enrollment

Registered

2018-05-21

Start date

Unknown

Completion date

Unknown

Last updated

2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- CARCINOMA CERVIX

Interventions

Intervention1: IG-VMAT: IMAGE GUIDED - VOLUMETRIC MODULATED ARC THERAPY Total duration : 4.5 weeks Frequency of treatment : Once daily Control Intervention1: 3D-CRT: 3 DIMENSIONAL CONFORMAL RADIOTHER

Eligibility

Inclusion criteria

Inclusion criteria: 1. Previously untreated, biopsy proven squamous cell carcinoma cervix 2. Karnofsky performance scale > 70 3. Pre treatment parameters: - a) HB > 10gm/dl b) Age c) TLC > 4000/cu mm d) Platelets > 1 lakh/cu mm e) Serum urea f) Serum creatinine g) Normal Chest X-ray 4. Patientâ??s willingness to give informed consent and agree to

Exclusion criteria

Exclusion criteria: 1. All post operative cases 2. Medical contraindication for concurrent chemotherapy 3. Patients with history of previous malignancies 4. Patients having any uncontrolled co-morbid conditions.

Design outcomes

Primary

Measure	Time frame
Acute toxicityTimepoint: Weekly during treatment	—

Secondary

Measure	Time frame
Dosimetric comparison of the doses to the organs at risk with 3D-CRT compared to IG-VMAT.Timepoint: Post completion of treatment	—

Countries

India

Contacts

Public ContactMANINDER SINGH

POST GRADUATE INSTITUTE OF MEDICAL EDUCATION AND RESEARCH

bhavana1035@gmail.com9814635706

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026