Effectiveness of Turmeric capsules comparing with intralesional Steroid injections in the treatment of habit related reduced mouth opening.

Comparison of Curcumin and intralesional Steroid injections in the management of oral submucous fibrosis: A clinical study.

Status

Recruiting

Phases

Phase 1Phase 2

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2018/05/013987

Enrollment

Registered

2018-05-21

Start date

Unknown

Completion date

Unknown

Last updated

2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- Patients who are suffering from Oral submucous fibrosis.

Interventions

Intervention1: Intralesional Steroid injections Curcumin capsules 1. To evaluate the efficacy of curcumin capsule in the management of OSMF. 2. To compare the curcumin capsule and intralesional injec

Eligibility

Inclusion criteria

Inclusion criteria: Patients within the age group of 20-40 years, with a histological diagnosis of Oral submucous fibrosis. Patients who had signed the informed consent on approved format.

Exclusion criteria

Exclusion criteria: Patients presenting with co existing malignancy/white lesions. Patients with known allergy to drugs. Patients who are previously treated for Oral submucous fibrosis. Patients not willing for biopsy. Patients with any systemic disease.

Design outcomes

Primary

Measure	Time frame
To compare the efficacy of Curcumin and in intralesional Steroid injections in the management of oral submucous fibrosis.Timepoint: 15 days for 3 months for curcumin capsules. Weekly for 3 months for intralesional Steroid injections.	—

Secondary

Measure	Time frame
To compare the Curcumin capsule and intralesional injection of Steroid in the management of OSMF with regard to: 1) Burning sensation. 2) Interincisal distance. 3) Tongue protrusion. 4) Cheek flexibility. Timepoint: 15 days for 3 months for curcumin capsules. Weekly for 3 months for intralesional Steroid injections.	—

Countries

India

Contacts

Public ContactBinika Laishram

The Oxford Dental College

bhatre_anu@hotmail.com9845303297

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026