Health Condition 1: null- Chronic respiratory patients with COPD and ILD. Trial for developing intervention that will prevent acute hypoxia induced maladies and improve functional exercise capacity
Conditions
Interventions
Intervention1: Exercise training, Ischemic pre-conditioning: Participants will continue their routine activity and medications and will also be provided structured exercise training with or without is
Sponsors
Dr Vishal Bansal
Eligibility
Inclusion criteria
Inclusion criteria: 1. All participants must have quit smoking at least eight weeks before inclusion into the study or are non-smokers. 2.Participants with a clinical diagnosis of moderate to severe chronic respiratory disease requiring enrollment into pulmonary rehabilitation program for their disease management. 3. Participants who have completed supervised pulmonary rehabilitation program at least three months earlier and require re-induction into the program for their management. 4.Participants on long term oxygen therapy, their detailed record of requirement and usage of such therapy shall be maintained. 5. All patient participants should be compliant to pharmacotherapy for their disease management at least one month prior to induction into the study to eliminate the confounding effect due to improvement imparted by pharmacotherapy. 6. All participants with anemia shall be given appropriate therapy to raise hemoglobin levels to normal prior to induction in the study.
Exclusion criteria
Exclusion criteria: 1.Patient participants having co-morbidities likely to affect the study parameters like Pulmonary artery hypertension, Obesity hypoventilation, cor pulmonale. 2.Exercise intolerance due to heart failure, angina pectoris, dyspnea of cardiac origin 3.Endocrinal disorders such as Diabetes mellitus, thyroid disorder which is likely to cause autonomic dysfunction. 4.Participants in both the groups having episode of acute infection in the month preceding induction into the study or during the study period and patients requiring course of oral steroids during the course of study shall be excluded from the study. 5.Physiological, musculoskeletal, neurological or psychological impairment impeding training program.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Main outcome of this study is to develop a protocol in which â??ischemic pre-conditioningâ?? will be added to the routine activity or a structured exercise program that will lead to increase in tolerance to hypoxia.Timepoint: 10 Weeks, improvement in tolerance to acute hypoxia exposure. 14 weeks, sustenance of improvement achieved in tolerance to acute hypoxia exposure | — |
Secondary
| Measure | Time frame |
|---|---|
| Improvement in functional exercise capacityTimepoint: 10 weeks, after structured exercise training. 14 weeks, sustenance of improvement in functional exercise capacity | — |
Countries
India
Contacts
Public ContactDr Vishal Bansal
Vallabhbhai Patel Chest Institute
Outcome results
None listed