Assessment of a Novel Method to Prevent MRSA Recurrence

MRSA Dermal Decolonization Study - MDDS

Status

Active, not recruiting

Phases

Phase 1Phase 2

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2018/05/013981

Enrollment

765

Registered

2018-05-21

Start date

Unknown

Completion date

Unknown

Last updated

2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Intervention1: Staphylococcus aureus 502A suspended in phosphate buffered saline: 502a is a naturally occurring strain of Staphylococcus Aureus that has previously been shown to have beneficial effec

Eligibility

Inclusion criteria

Inclusion criteria: Microbiological test results showing MRSA colonization, such as positive CHROMagar• MRSA plate reading

Exclusion criteria

Exclusion criteria: 1. cancer 2. autoimmune disease 3. congenital immunodeficiencies 4. uncontrolled diabetes mellitus 5. breast-feeding women or women who were or might become pregnant during the study period 6. known history of HIV infection 7. concurrent and chronic therapy with immunosuppressive drugs 8. receipt of a live-virus vaccine during the last 2 months 9. recent use of corticosteroids or other immunosuppressive medications 10. eczema 11. psoriasis 12. atopic dermatitis 13. seborrheic dermatitis 14. drug eruptions 15. rosacea, hives (urticaria) > dry skin (xerosis) 16. administration/consumption of topical or systemic antibiotics in the last 14 days 17. active psychiatric disease 18. history of major depression, psychosis, or in-patient hospitalization for psychiatric management.

Design outcomes

Primary

Measure	Time frame
MRSA colonization recurrence rate. After participants have been confirmed as MRSA negative on Day 1, recurrence is defined as the presence of greater than 24 CFUs in a selective growth media MRSA test (such as CHROMagarâ?¢ MRSA) and in any one of the four sites sampled at each time point (hand, throat, axilla, and nares).Timepoint: Day 0, Day 1, week 4, and week 8	—

Secondary

Measure	Time frame
MRSA colonization recurrence rate. After participants have been confirmed as MRSA negative on Day 1, recurrence is defined as the presence of greater than 24 CFUs in a selective growth media MRSA test (such as CHROMagarâ?¢ MRSA) and in any one of the four sites sampled at each time point (hand, throat, axilla, and nares).Timepoint: Day 0, Day 1, and weekly thereafter through week 26	—

Countries

India

Contacts

Public ContactLove Aggarwal

Metro Hospital

Vijnt1@gmail.com9219889278

Outcome results