Health Condition 1: null- ASA I & II patients, between age group18-60yrs with BMI of 30kg/m2 and above, undergoing elective laparoscopic surgery under general anaesthesia for atleast 30 minutes and maximum of 3 hours
Conditions
Interventions
Intervention1: Intravenous dexmedetomidine: Intravenous dexmedetomidine calculated as per the Ideal Body weight as a bolus dose of 1microgram/kg prior to induction of anaesthesia followed by infusio
Sponsors
Dr L H Hiranandani Hospital
Eligibility
Inclusion criteria
Inclusion criteria: 1 Patients undergoing elective laparoscopic surgery 2 With BMI between 30kg/m2 and above 3 ASA 1and 2 under general anaesthesia 4 Duration of 30 minutes to maximum of 3 hours 5 Informed consent
Exclusion criteria
Exclusion criteria: 1.History of significant cardiac pulmonary, liver or renal disease. 2. Patient scheduled for awake bronchoscopic intubation. 3. Previous history of cerebrovascular accident, other neurological disorders and those on long term drugs affecting CNS (chronic BZDâ??s/ opioids) 4. Allergy to dexmedetomidine . 5. Patients with significant hemodynamic changes intraoperatively, fall of Mean arterial blood pressure by more than 20% of baseline, 6. Intraoperative entropy of more than 60 for more than 10 minutes
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The ideal weight scalar for assessing dose of intravenous dexmedetomidine for the haemodynamic stability during general anaesthesia during the duration of laprascopic surgeryTimepoint: Intraoperatively during surgery | — |
Secondary
| Measure | Time frame |
|---|---|
| Recovery parameters like 1 Sedation score post extubation 2 Time for extubation after stoping dexmedetomidine infusion 3. Time for eye opening after stopping dexmedetomidine infusion 4. Time for obeying oral commands after stopping dexmedetomidine infusion 5. Time to achieve entropy values more than 90 after stopping dexmedetomidine infusion 6. Consumption of sevoflurane at the end of surgeryTimepoint: 1. Sedation score - post extubation 2. Time for extubation - time required after stopping dexmedetomidine infusion to the time of extubation 3. Time for eye opening after stopping dexmedetomidine infusion to the time of extubation 4. Time for obeying oral commands after stopping dexmedetomidine infusion to the time of extubation 5. Time taken to achieve entropy values more than 90 after stopping dexmedetomidine infusion 6. Consumption of sevoflurane at the end of surgery | — |
Countries
India
Contacts
Public ContactDr Meenoti Potdar
Dr L H Hiranandani Hospital
Outcome results
None listed