Muscle Relaxants in Anaesthesia

A comparison on the effects of Rocuronium and Vecuronium on tracheal intubation and maintainence of anaesthesia among patients undergoing elective surgery

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2018/05/013838

Enrollment

Registered

2018-05-11

Start date

Unknown

Completion date

Unknown

Last updated

2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- The Effect of MUSCLE RELAXANTS during Anaesthesia

Interventions

Intervention1: ROCURONIUM: Rocuronium 0.6mg/kg initially during induction of aneasthesia and 0.15mg/kg top up maintenance dose during duration of surgery Control Intervention1: VECURONIUM: Vecuronium

Eligibility

Inclusion criteria

Inclusion criteria: 1. Age 18-50 years 2. ASA Grade 1 or 2 3.Mallampati class 1 or 2. 4. Patients who underwent elective major surgeries

Exclusion criteria

Exclusion criteria: 1. Allergic to study medication 2. Mallampatti 3 and 4 3. Patent Refusal 4. Requiring Rapid Sequence Induction, GERD 5. With history of cardiovascular or renal pathologies 6. With history of neuromuscular disorders or on drugs influencing neuromuscular function 7. Pregnant patients

Design outcomes

Secondary

Measure	Time frame
HaemodynamicsTimepoint: twice in first 15 minutes, then every 15 minutes	—

Primary

Measure	Time frame
Onset and Duration of Action of Muscle relaxantsTimepoint: Onset of action : every 30 seconds after drug administration. Duration of Action: every 5 minutes	—

Countries

India

Contacts

Public ContactDr Sankar Mohan

Sree Gokulam Medical College And Research Foundation

drvenuanst@gmail.com04723041000

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026