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use of melatonin to decrease the hemodynamic responses to laryngoscopy and intubation

A prospective, randomized, double blinded study to assess the efficacy of melatonin in attenuation of hemodynamic responses to laryngoscopy and intubation

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2018/05/013835
Enrollment
100
Registered
2018-05-11
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- decreasing laryngoscopy and intubation response in patients coming for general anesthesia

Interventions

Intervention1: vitamin d: similar looking placebo tablets Control Intervention1: melatonin for intubation response: melatonin 6mg tablet for reducing laryngoscopy and intubation response

Sponsors

Sri Ramachandra University
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Only ASA 1 and 2 patients coming for general anesthesia for surgeries longer than 30 minutes

Exclusion criteria

Exclusion criteria: Diabetes Hypertension Psychiatric illness Intake of anti-psychotics, sedatives, anxiolytics drugs Sleep disorders Allergy to study drugs Anticipated difficult airway Pregnant and lactating females

Design outcomes

Primary

MeasureTime frame
outcome-To study the changes in blood pressure in response to laryngoscopy and intubationTimepoint: At 1,5,10 and 20 minutes—

Secondary

MeasureTime frame
To monitor any adverse effects during the study period.Timepoint: nil—

Countries

India

Contacts

Public ContactThamarai selvi

Sri Ramachandra University

thames25@gmail.com04423860830

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026