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Role of chemicals in urine for predicting renal failure in patients with muscle injury

Evaluation of Urinary Biomarkers TIMP-2 and IGFBP7 for early prediction of acute kidney injury after traumatic crush injuries

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2018/05/013824
Enrollment
70
Registered
2018-05-11
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- Admitted to ICU with crush injuries

Interventions

None listed

Sponsors

AIIMS intramural fund
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: subjects- 70 adult patients [ age > 18 years to 65 years] admitted to Surgical Trauma Critical Care unit following crush injury to lower limb after trauma will be included in the study.

Exclusion criteria

Exclusion criteria: Patients less than 18 years of age, Patients with established AKI Patients with chronic kidney disease

Design outcomes

Primary

MeasureTime frame
evaluate TIMP-2 in combination with IGFBP-7 ([TIMP-2]Ã?[IGFBP7] as an adequate diagnostic test to identify early AKI after traumatic crush injuries.Timepoint: The primary endpoint will be the new occurrence of acute kidney injury stage 2 or 3 within 48 h after admission to ICU.—

Secondary

MeasureTime frame
noneTimepoint: none—

Countries

India

Contacts

Public ContactDR RICHA AGGARWAL

Associate professor, critical and intensive care, JPNATC,AIIMS

pathakricha@yahoo.co.in9873731042

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026