To estimate and compare blood sugar levels and a biomarker in gingival fluid in gum disease patients with diabetes before and after teeth cleaning and laser treatment.

Effect of low level laser therapy as an adjunct to scaling and root planing on TNF-ALPHA in gingival crevicular fluid and glycosylated hemoglobin (HbA1c) levels in type 2 diabetic patients with chronic generalized periodontitis- a clinicobiochemical study.

Status

Recruiting

Phases

Phase 1

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2018/05/013807

Enrollment

Registered

2018-05-11

Start date

Unknown

Completion date

Unknown

Last updated

2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- CHRONIC PERIODONTITIS PATIENTS WITH TYPE 1 DIABETES MELLITUS

Interventions

Intervention1: Scaling and root planing and laser biostimulation.: Scaling and root planing to remove deposits from teeth surfaces once. Laser biostimulation for pocket reduction was done at baseline

Eligibility

Inclusion criteria

Inclusion criteria: 1. Patients 30 years or more with chronic periodontitis having probing pocket depth >= 5mm. 2. Patients having 20 or more teeth. 3. Physician diagnosed type 2 diabetes of more than 3 months duration. 4. Currently under the care of a physician for diabetes management. 5. No change in diabetes related medications during 3 months prior to enrollment. 6. Screening HbA1c values within the range of 6% to 7%. 7. No definitive periodontal treatment during 6 months prior to enrollment.

Exclusion criteria

Exclusion criteria: 1.Patients suffering from any known systemic disease other than diabetes like renal disorders, anemia, hyperthyroidism, etc. 2.Patients who had a physician visit within the last 30 days because of hyperglycemia or diabetes related complications. 3.Chronic or continuous use of non-steroidal anti-inflammatory drugs within the preceeding two months. 4. Patients under systemic antibiotics, corticosteroids or immunosuppressive drugs. 5. Pregnant women or lactating women. 6.Subjects who are smokers, tobacco or alcohol users.

Design outcomes

Primary

Measure	Time frame
Reduction in HbA1c levels and TNF-ALPHA levels in chronic periodontitis patients with diabetes after scaling and root planing along with laser biostimulation.Timepoint: 1,7,30,90,180	—

Secondary

Measure	Time frame
Reduction in inflammation, blood sugar level and patient comfort.Timepoint: 1,7,30,90,180 days	—

Countries

India

Contacts

Public ContactDR PRINCY ANNA MATHEW

COORG INSTITUTE OF DENTAL SCIENCE

radika_b24@yahoo.co.in9742096982

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026