Skip to content

Effects on airway configuration of 2 different types of drugs used for sedation in children undergoing MRI

Effect of sedation for Magnetic resonance imaging on airway configuration in children: comparison of propofol alone vs propofol with single dose ketamine â?? A randomized controlled trial - PROKETMRI

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2018/05/013798
Enrollment
58
Registered
2018-05-09
Start date
Unknown
Completion date
Unknown
Last updated
2023-03-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- paediatric Patients intravenous receiving sedation for undergoing magnetic resonance imaging

Interventions

Intervention1: Propofol and ketamine: One group of paediatric patients will be given 0.5mg/kg of ketamine before propofol sedation Control Intervention1: Propofol in another group: Propofol titrated t

Sponsors

intramural funds JIPMER
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Children of age group 1 year to 6 years undergoing MRI brain and belonging to American Society of Anaesthesiologists (ASA) physical status classification 1 and 2.

Exclusion criteria

Exclusion criteria: Children with airway and craniofacial anomalies Children with congenital heart disease Children with h/o gastroesophageal reflux disease Children with h/o uncontrolled seizure disease Children with recent sedation

Design outcomes

Primary

MeasureTime frame
1.Measurement and comparison of upper airway cross sectional areaand diameters at level of soft palate, base of tongue and epiglottis during inspiration and expirationTimepoint: 1.Measurement and comparison of upper airway cross sectional areaand diameters at level of soft palate, base of tongue and epiglottis during inspiration and expiration

Secondary

MeasureTime frame
Comparison of recovery time as assessed by Ramsay sedation score to reach 2 or more 2.Requirement of rescue and total dose of propofol 3. Procedural complication and Post procedure vomiting 4. Discharge time (To reach Aldrete score of 9) 5.Quality of MRI image obtained Timepoint: at the end pf the procedure

Countries

India

Contacts

Public ContactDr Sakthirajan P

Jawaharlal Institute of Post Graduate Medical Education and Research

sakthiab8@gmail.com8903468132

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026