Clinical trial of Karappan in adults.

A Comparative Clinical trial of Siddha formulation of Nilavaagai Chooranam internally and Thengaai Thylam externally in the treatment of Karappan (Eczema) with and without Leech therapy.

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2018/05/013794

Enrollment

Registered

2018-05-09

Start date

Unknown

Completion date

Unknown

Last updated

2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- Patients with Clinical features like Itching, Oozing, Erythema, Papules, Vesicles, Scaling and Hyperpigmentation

Interventions

Intervention1: NILAVAAGAI CHOORANAM (internal) and THENGAAI THYLAM (external): NILAVAAGAI CHOORANAM is a herbomineral formulation in a dosage of 1g (bd) for 48 days. THENGAAI THYLAM externally in the

Eligibility

Inclusion criteria

Inclusion criteria: 1.Clinical features like Itching, Oozing, Erythema, Papules, Vesicles, Scaling and Hyperpigmentation. 2.Patients who are willing to undergo Leech application.

Exclusion criteria

Exclusion criteria: 1.Hypertension and other Cardiac ailments 2.Narcotics 3.Pregnancy and Lactation 4.Evidence of any skin disease other than eczema 5.Hemophilia 6.Thrombocytopenia 7.Hepatitis B 8.HIV 9.Renal Diseases 10.Severe anaemia 11.Immuno deficiency diseases

Design outcomes

Primary

Measure	Time frame
Efficacy of the trial drug measured by EASI scoreTimepoint: 1-48 days	—

Secondary

Measure	Time frame
To study the Siddha basic principles towards effect of medicine and therapy.Timepoint: 1-48 days	—

Countries

India

Contacts

Public ContactDr D Periyasami

National Institute Of Siddha,Tambaram Sanatorium,chennai

njmuthu@hotmail.com9962006843

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026